What is Fentanyl used for | What County

What is Fentanyl used for

The active ingredient fentanyl is one of the most important remedies for severe to very severe pain. It is about 125 times more potent than morphine. Fentanyl is particularly used for breakthrough pain in the course of cancer and severe chronic pain. Various dosage forms such as nasal spray, lozenges and patches are available for this purpose. Here you can read everything important about Fentanyl, dosage, effect and application.

What is Fentanyl used for
What is Fentanyl used for
Fentanyl used for
Fentanyl used for

Fentanyl is one of the opioid analgesics. It is used primarily for severe pain, such as chronic tumor pain, polytrauma, burns and fractures. It is 100 times more potent than morphine. In addition to its analgesic use, it is also suitable in higher doses as a narcotic in anesthesia.

Working mechanism
Opioid analgesics act via so-called opioid receptors. The lipophilic fentanyl binds mainly to the μ-opioid receptor on cell surfaces. Since this type of receptor is found in many places in the body, fentanyl has both a central and peripheral effect.

In the periphery, it prevents sensory nerve endings from being able to form or transmit excitations. On the spinal and supraspinal level, it intervenes in the pain pathways and modulates, among other things, the sensation of pain. Via opioid receptors in the brain, fentanyl is also sedative, comatose in high doses.

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